saxenda glp-1 diabetes market impact share of RAs in 2016 and 2017 GLP-1 Receptor Agonist Market Forecast

GLP-1 (glucagon-like peptide-1) is a gut hormone that signals fullness to the brain, slows gastric emptying, and plays a role in blood sugar regulation

On average, patients can expect to lose 1-3 pounds per week, though individual outcomes may vary

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression

Because of this, Novo does not believe the pill will replace injectables

We utilised a 1:1 propensity matching strategy to establish comparable groups of patients treated with different glucose-lowering drugs, including GLP-1RA, SGLT2 inhibitors and metformin